Dysphagia profiles after primary transoral robotic surgery or radiation for oropharyngeal cancer: A registry analysis. Issue 10 (3rd June 2021)

• Record Type: Journal Article
• Authors: Barbon, Carly E. A.; Yao, Christopher M. K. L.; Alvarez, Clare P.; Goepfert, Ryan P.; Fuller, Clifton D.; Lai, Stephen Y.; Gross, Neil D.; Hutcheson, Katherine A.
• Is Part Of: Head & neck. Volume 43:Issue 10(2021)
• Page Start: 2883
• Page End: 2895
• Publication Date: 2021-06-03
• Subjects: dysphagia -- head and neck cancer -- radiation -- surgery; Head -- Diseases -- Periodicals; Neck -- Diseases -- Periodicals; Head -- Periodicals; Neck -- Periodicals; Face -- Periodicals; 617.51059
• DOI: 10.1002/hed.26768
• Languages: English
• ISSNs: 1043-3074

Abstract

Abstract: Objective: To describe the physiologic swallowing impairments (MBSImP™©) associated with safety/efficiency impairments (DIGESTsafety /DIGESTefficiency grades) at 3–6 months after transoral robotic surgery (TORS) or radiation therapy (RT). Study Design: Secondary analysis of registry data. Setting: Single, academic institution. Methods: Two hundred and fifty‐seven patients with HPV+ oropharynx cancer were stratified by primary treatment (75 TORS, 182 RT). Modified barium swallow studies were analyzed at baseline and 3–6 months using MBSImP scores and DIGESTsafety /DIGESTefficiency grades. DIGESTsafety /DIGESTefficiency grades and MBSImP were compared groupwise and associations between DIGESTsafety /DIGESTefficiency grades and MBSImP were explored by ordinal logistic regression. Exploratory analyses were stratified by multimodality treatment. Results: Neither DIGESTsafety /DIGESTefficiency differed significantly between groups at baseline or 3–6 months. Laryngeal vestibule closure was impaired more frequently in the RT group (RT: 41% vs. TORS: 27%; p = 0.02) while the TORS group had significantly more pharyngeal contraction impairment (63%; p < 0.001) compared to RT at 3–6 months. Conclusion: The results suggest a focal injury associated with DIGESTsafety /DIGESTefficiency post‐TORS in contrast to a low‐level diffuse physiologic impairment associated with post‐RT dysphagia.