CP-040 Total parenteral nutrition: Do we accomplish the recommendations?. (14th February 2016)

• Record Type: Journal Article
• Authors: Betancor, T; Fraile, C; Navarro, M; Plasencia, I; Merino, J
• Is Part Of: European journal of hospital pharmacy. Volume 23(2016)Supplement 1
• Page Start: A17
• Page End: A18
• Publication Date: 2016-02-14
• Subjects: Pharmacy -- Periodicals; Hospital pharmacies -- Periodicals; 615.1
• DOI: 10.1136/ejhpharm-2016-000875.40
• Languages: English
• ISSNs: 2047-9956

Abstract

Abstract : Background: Total parenteral nutrition (TPN) must supply all of the daily nutritional requirements of a patient. This may be difficult to achieve, especially when peripheral access is used. Purpose: The aim of our study was to verify if ESPEN recommendations about macronutrient content of TPN were accomplished in routine clinical practice. Material and methods: TPN prescriptions between 1 January 2015 and 30 April 2015 were located using the intranet of the hospital. Macronutrient content (proteins, lipids and glucose) was analysed considering the weight of the patient, and classified according to administration access (peripheral or central). In addition, the content of protein in central TPN prescriptions was analysed considering the subgroup of patients (surgical or medical). To collect these data, MedicalOne Parenteral software was used. Results: We analysed 567 TPN prescriptions, 85% central access and 15% peripheral access. Median content of macronutrients and number of TPN that included new generation products (omega 3 enriched lipids and glutamine) are shown in the table. Of the 485 central TPN prescriptions, 46.4% (n = 225) were for surgical patients and rest (n = 260) for medical patients (73 of these prescriptions were for oncological patients). Median protein prescribed in these three subgroups of patients was 1.3 g/kg, 1.2 g/kg and 1.1 g/kg, respectively. Conclusion: Protein and glucose content was lower in peripheral TPN than in central TPN due to osmolarity restriction. New generation products (omega 3 enriched lipids and glutamine) were highly prescribed in central TPN. Recommended protein content was not achieved; ESPEN guidelines recommend more than 1.5 g/k of proteins in surgical patients 1 and at least 1.2 g/kg in oncological patients 2 but in our routine clinical practice, only 1.3 g/kg and 1.1 g/kg, respectively, were prescribed. References and/or Acknowledgements: ESPEN Guidelines on Parenteral Nutrition: Surgery. M Braga, O Ljungqvist, P Soeters, K Fearon, A Weimann, F Bozzetti ESPEN Guidelines on Parenteral Nutrition: Non-surgical oncology. F Bozzetti, J Arends, K Lundholm, A Micklewright, G Zurcher, M Muscaritoli No conflict of interest.