Reversal of Folate Malabsorption in Tropical and Non-tropical Sprue by Calf Jejunum. Issue 5616 (24th August 1968)

• Record Type: Journal Article
• Authors: Baker, H.; Frank, O.; Ziffer, H.; Feingold, S.; Cintron-Rivera, A. A.
• Is Part Of: BMJ. Volume 3:Issue 5616(1968)
• Page Start: 472
• Page End: 474
• Publication Date: 1968-08-24
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.3.5616.472
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : In eight patients with folic acid malabsorption the malabsorption was reversed only when a combination of either 250 mg. of lyophilized human jejunal juice or 5 g. of lyophilized calf jejunum with 5 mg. of synthetic folic acid was fed; calf liver was ineffective. The factors in calf jejunum that re-established folic acid absorption were heat-stable and did not form polyglutamyl folates on previous incubation with folic acid.