A systematic review of symptomatic outcomes used in oesophagitis drug therapy trials. (13th April 2004)

• Record Type: Journal Article
• Authors: Sharma, N; Donnellan, C; Preston, C; Delaney, B; Duckett, G; Moayyedi, P
• Is Part Of: Gut. Volume 53(2004)Supplement 4
• Page Start: iv58
• Page End: iv65
• Publication Date: 2004-04-13
• Subjects: gastro-oesophageal reflux disease -- healing of oesophagitis -- heartburn -- symptom frequency -- symptom severity; GORD, gastro-oesophageal reflux disease -- PGWBI, psychological general well being index -- SF-36, short form 36; Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gut.2003.034371
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : Symptoms are an important outcome for measurement in clinical trials into gastro-oesophageal reflux disease, but the optimal approach to symptom assessment has not been formally evaluated. The authors conducted a systematic review to assess how reflux symptoms have been evaluated and how well these correlate with oesophagitis healing and relapse.