Reliability and validity of the Taiwanese version of the Neurological Disorders Depression Inventory for Epilepsy (Tw-NDDI-E). (October 2020)

• Record Type: Journal Article
• Authors: Shih, Yen-Cheng; Chou, Chien-Chen; Lu, Yi-Jiun; Chou, Yuan-Hwa; Yu, Hsiang-Yu
• Is Part Of: Seizure. Volume 81(2020)
• Page Start: 53
• Page End: 57
• Publication Date: 2020-10
• Subjects: Epilepsy -- Depression -- NDDI-E -- Taiwanese; Epilepsy -- Periodicals; Epilepsy -- Periodicals; Seizures -- Periodicals; Épilepsie -- Périodiques; Electronic journals; Electronic journals; 616.853
• DOI: 10.1016/j.seizure.2020.07.025
• Languages: English
• ISSNs: 1059-1311

Abstract

Highlights: The Chinese version of the NIDD-E is a good screening tool for depression in patients with epilepsy in Taiwan. The Chinese NIDD-E was validated with objective and subjective psychometric tools. The optimal cut-off score for the NDDI-E in the Taiwanese population is 15. The cut-off score on the NDDI-E varied by region despite the use of the same language. Abstract: Introduction: Depression is the most commonly seen psychiatric co-morbidity of epilepsy. Depression in patients with epilepsy (PWE) is underrecognized. The Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) is a useful tool to screen for major depressive episodes (MDEs) in PWE. This study validated the Taiwanese version of the NDDI-E using data from adult PWE in our hospital. Method: PWE were recruited from the Taipei Veterans General Hospital from April 2017 to December 2019. The Chinese version of the NDDI-E for the Taiwanese population and the Beck Depression Inventory-II (BDI-II) were completed as part of the self-rated psychiatric assessments. The mood disorder module of the Mini International Neuropsychiatric Interview (MINI) was completed as part of the psychiatric assessment before the self-rated assessment. Internal consistency, external validation, and receiver operator characteristic (ROC) curve analysis were used to assess the utility of the Taiwanese version of the NDDI-E. Results: We recruited 109 patients during the 33-month study period. The mean age was 33.1 ± 8.94 years old. The mean NDDI-E score was 12.32 ± 4.96. The mean BDI-II score was 13.26 ± 12.77. All NDDI-E items were significantly positively associated with the corrected overall NDDI-E score (Cronbach's alpha = 0.902, r = 0.825, p < 0.0001). The cut-off point for the NDDI-E determined with receiver operating characteristic (ROC) curve analysis is 15 (sensitivity = 85.0%, specificity = 87.64%). Conclusion: The Chinese version of the NDDI-E adapted for the Taiwanese population is a reliable and valid self-reported questionnaire for detecting MDE in Taiwanese PWE.