"On-Off" Phenomena Related to High Plasma Levodopa. Issue 5867 (16th June 1973)
- Record Type:
- Journal Article
- Title:
- "On-Off" Phenomena Related to High Plasma Levodopa. Issue 5867 (16th June 1973)
- Main Title:
- "On-Off" Phenomena Related to High Plasma Levodopa
- Authors:
- Claveria, L. E.
Calne, D. B.
Allen, J. G. - Abstract:
- Abstract : The neurological deficit and plasma concentrations of levodopa have been studied in a Parkinsonian patient experiencing "on-off" phenomena. Blind evaluations of transient attacks of dysphonia revealed an association between episodes of neurological deterioration and exceptionally high plasma concentrations of levodopa shortly after ingestion. These results indicate that "on-off" phenomena can be toxic reactions to levodopa rather than deteriorations due to inadequate intake or absorption of the drug. Management of patients subject to such attacks should be aimed at minimizing fluctuations in the serum level of the drug.
- Is Part Of:
- BMJ. Volume 2:Issue 5867(1973)
- Journal:
- BMJ
- Issue:
- Volume 2:Issue 5867(1973)
- Issue Display:
- Volume 2, Issue 5867 (1973)
- Year:
- 1973
- Volume:
- 2
- Issue:
- 5867
- Issue Sort Value:
- 1973-0002-5867-0000
- Page Start:
- 641
- Page End:
- 643
- Publication Date:
- 1973-06-16
- Subjects:
- Medicine -- Periodicals
Medicine -- Periodicals
Medicine
Periodicals
610 - Journal URLs:
- http://www.bmj.com/archive ↗
http://www.jstor.org/journals/09598138.html ↗
http://www.ncbi.nlm.nih.gov/pmc/journals/3/ ↗
http://www.bmj.com/bmj/ ↗
http://www.bmj.com/archive ↗ - DOI:
- 10.1136/bmj.2.5867.641 ↗
- Languages:
- English
- ISSNs:
- 0007-1447
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 18980.xml