A Randomized Controlled Trial of Acetyl Salicyclic Acid in the Secondary Prevention of Mortality from Myocardial Infarction. Issue 5905 (9th March 1974)

• Record Type: Journal Article
• Authors: Elwood, P. C.; Cochrane, A. L.; Burr, M. L.; Sweetnam, P. M.; Williams, G.; Welsby, E.; Hughes, S. J.; Renton, R.
• Is Part Of: BMJ. Volume 1:Issue 5905(1974)
• Page Start: 436
• Page End: 440
• Publication Date: 1974-03-09
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.1.5905.436
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : The results of a randomized controlled trial of a single daily dose of acetyl salicylic acid (aspirin) in the prevention of reinfarction in 1, 239 men who had had a recent myocardial infarct were statistically inconclusive. Nevertheless, they showed a reduction in total mortality of 12% at six months and 25% at twelve months after admission to the trial. Further trials are urgently required to establish whether or not this effect is real.