Association of Serious Hypoglycemic Events in Older Adults With Changes in Glycemic Performance Measures. Issue 7 (July 2021)

• Record Type: Journal Article
• Authors: Tseng, Chin-Lin; Pogach, Leonard M.; Lu, Shou-En; Soroka, Orysya; Aron, David C.
• Is Part Of: Medical care. Volume 59:Issue 7(2021)
• Publication Date: 2021-07
• Subjects: diabetes -- hypoglycemia -- hemoglobin A1c -- patient safety -- health policy; Economics, Medical -- Periodicals; Insurance, Health -- Periodicals; Santé, Services de -- Administration -- Périodiques; Soins médicaux -- Périodiques; Medical economics -- Periodicals; Health insurance -- Periodicals; Medical economics -- United States -- Periodicals; Health insurance -- United States -- Periodicals; Comprehensive Health Care -- Periodicals; Personal Health Services -- Periodicals; Gezondheidszorg; Économie de la santé -- Périodiques; Santé, Services de -- Périodiques; Health insurance; Medical economics; United States; Periodicals; 362.10973
• DOI: 10.1097/MLR.0000000000001528
• Languages: English
• ISSNs: 0025-7079

Abstract

Abstract : Background: Reducing serious hypoglycemic events is a Federal-wide objective. Despite studies of trends for rates of serious hypoglycemia in existing literature, rigorous evaluation of links between the observed trends and changes in professional guidelines or performance measures for glycemic control is lacking. Objective: To evaluate whether changes in professional society guidelines and performance measures for glycemic control correspond to changes in rates of serous hypoglycemia. Research Design: This was a retrospective observational study. We merged Veterans Health Administration (VHA) and Medicare patient-level databases of VHA patients and identified those aged 65 years and above and receiving hypoglycemic agents. We derived age-adjusted and sex-adjusted annual rates and constructed piecewise Poisson regression models adjusting for age and sex to assess time trends of the rates. Subjects: VHA patients, 2002–2015. Measures: The main outcome was the annual rates (2004–2015) of serious hypoglycemia, defined as hypoglycemia-related emergency department visits or hospitalizations. Secondary outcomes were annual rates of hemoglobin (Hb) A1c level <7% and >9%. Age and sex were additional variables. Results: The annual rate for hypoglycemia decreased by 4.8% (rate ratio: 0.952; 95% confidence interval, 0.949–0.956) for 2008–2015 but did not change (1.001; 0.994–1.001) in 2004–2008. In 2008–2015, the annual rate for HbA1c <7% decreased by 5.0% (0.950; 0.949–0.951) but for HbA1c >9%, increased by 7.9% (1.079; 1.076–1.082). Conclusion: The cooccurrence of decreasing rates for HbA1c<7% and serious hypoglycemia since 2008 supports the possibility that withdrawal of a <7% HbA1c measure in 2008 impacted clinical practice and patient outcomes.