Concurrent Stroke and Myocardial Infarction After Mild COVID-19 Infection. Issue 3 (May 2021)

• Record Type: Journal Article
• Authors: Ruiz-Ares, Gerardo; Jimenez-Valero, Santiago; Fernández-Prieto, Andrés; Arbas-Redondo, Emilio; Díaz-Pollán, Beatriz; Navia, Pedro; Meras, Pablo; Alonso de Leciñana, Maria; de Donebún, Jorge R.P.; Rigual, Ricardo; Fuentes, Blanca; Díez-Tejedor, Exuperio
• Is Part Of: Neurologist. Volume 26:Issue 3(2021)
• Publication Date: 2021-05
• Subjects: stroke -- COVID-19 -- hypercoagulation state -- myocardial infarction -- thrombolysis; Nervous System Diseases -- Periodicals; Nervous system -- Diseases -- Periodicals; Neurologie; 616.8
• DOI: 10.1097/NRL.0000000000000311
• Languages: English
• ISSNs: 1074-7931

Abstract

Abstract : Introduction: The concurrency of both, acute stroke and acute myocardial infarction in normal conditions, outside the pandemic is rare. Coagulopathy has been associated with the inflammatory phase of coronavirus disease (COVID-19) and might be involved in this concurrency. Cases Report: We describe 2 patients with previous mild or no symptoms of COVID-19, admitted for acute stroke with recent/simultaneous myocardial infarction in whom admission polymerase chain reaction was negative but serologic testing diagnosed COVID-19. In these patients, concurrent stroke and myocardial infarction could have been promoted by COVID-19 infection. Management and evolution are detailed, and their contacts to confirm the COVID-19 infection. Pathogenic analysis of possible hypercoagulation state is described suggesting the hypothesis of endothelial dysfunction as the strongest mechanism involved in thrombus formation after the acute phase of COVID-19 infection. Conclusions: Our experience with these cases suggests that patients with mild symptoms can also present thromboembolic complications once the acute phase of COVID-19 infection has passed.