Magnesium Sulphate for Fetal Neuroprotection at Imminent Risk for Preterm Delivery: A Systematic Review With Meta-analysis and Trial Sequential Analysis. Issue 2 (June 2021)

• Record Type: Journal Article
• Authors: Wolf, H.T.; Huusom, L.D.; Henriksen, T.B.; Hegaard, H.K.; Brok, J.; Pinborg, A.
• Is Part Of: Obstetric anesthesia digest. Volume 41:Issue 2(2021)
• Publication Date: 2021-06
• Subjects: Neonatal Morbidity and Mortality -- Pharmacology; Anesthesia in obstetrics -- Periodicals; Anesthesia in obstetrics -- Abstracts -- Periodicals; 617.968205
• DOI: 10.1097/01.aoa.0000744024.18436.f5
• Languages: English
• ISSNs: 0275-665X

Abstract

Abstract : ( BJOG . 2020;127:1180–1188) Preterm birth is associated with higher risk of cerebral palsy (CP) and other complications. Magnesium sulfate (MgSO4) may decrease risk of CP when taken immediately before preterm birth. A recent trial investigated the neuroprotective functions of MgSO4 . This updated systematic review, meta-analysis and trial sequential analysis (TSA) assessed the effects of MgSO4 administered before preterm birth to prevent CP in neonates.