Universal Screening for Lynch Syndrome in Uterine Cancer Patients: A Quality Improvement Initiative. Issue 4 (April 2021)

• Record Type: Journal Article
• Authors: Spinosa, Daniel; Acosta, Tatiana; Wong, Janice; Kurtovic, Kelli; Mewshaw, Jennifer; Collins, Sarah; Kauff, Noah; Havrilesky, Laura J.; Strickland, Kyle C.; Previs, Rebecca A.
• Is Part Of: Obstetrical & gynecological survey. Volume 76:Issue 4(2021)
• Publication Date: 2021-04
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; Generative organs, Female -- Surgery -- Periodicals; 618
• DOI: 10.1097/01.ogx.0000742224.68804.f6
• Languages: English
• ISSNs: 0029-7828

Abstract

Abstract : (Abstracted from Gynecol Oncol 2021;160:169–174) The Society of Gynecologic Oncology (SGO) recommends systematic clinical screening for Lynch syndrome through immunohistochemistry (IHC) testing of tumors identified in patients younger than 60 years or of any age and a thorough review of personal and family history. Testing targets expression of mismatch repair genes MLH1, MLH2, PMS2, and MSH6 to evaluate microsatellite instability.