Ketotifen in adult asthma. Issue 6211 (9th February 1980)

• Record Type: Journal Article
• Authors: Dyson, A J; Mackay, A D
• Is Part Of: BMJ. Volume 280:Issue 6211(1980)
• Page Start: 360
• Page End: 361
• Publication Date: 1980-02-09
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.280.6211.360
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : The efficacy and adverse effects of ketotifen 1 mg twice daily and 2 mg twice daily were compared with placebo in 50 patients with atopic asthma in a multicentre, double-blind study. Ketotifen in the higher dosage caused a slight reduction in salbutamol usage and a modest improvement in breathing in patients not already receiving inhaled corticosteroids. The drug was ineffective in patients receiving inhaled corticosteroids. Drowsiness was a troublesome effect causing withdrawal from treatment or reduction of dosage in seven patients while receiving ketotifen compared with only three while receiving placebo.