Resetting of osmoreceptor response as cause of hyponatraemia in acute idiopathic polyneuritis. Issue 6203 (8th December 1979)

• Record Type: Journal Article
• Authors: Penney, M D; Murphy, D; Walters, G
• Is Part Of: BMJ. Volume 2:Issue 6203(1979)
• Page Start: 1474
• Page End: 1476
• Publication Date: 1979-12-08
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.2.6203.1474
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : In a patient with hyponatraemia associated with acute idiopathic polyneuritis plasma concentrations of antidiuretic hormone increased when hypertonic saline was infused intravenously, and urine osmolality rose concomitantly. A water load was excreted normally, while the plasma remained extremely hypo-osmolal. It is concluded that osmoregulation was functioning normally but was set abnormally low, possibly owing to a disturbance of the peripheral volume receptors.