Exercise Asthma and Disodium Cromoglycate. Issue 5731 (7th November 1970)

• Record Type: Journal Article
• Authors: Poppius, H.; Muittari, A.; Kreus, K.-E.; Korhonen, O.; Viljanen, A.
• Is Part Of: BMJ. Volume 4:Issue 5731(1970)
• Page Start: 337
• Page End: 339
• Publication Date: 1970-11-07
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.4.5731.337
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : Exercise-induced asthma (defined as a fall in PEF of at least 25% of the pre-exercise value) was studied in adult patients with uncomplicated asthma. This was found to occur in 22 out of 52 patients. Pre-exercise inhalation of disodium cromoglycate reduced the mean fall in PEF after maximal exercise from 50% of the pre-exercise value to 23% (open assessment in 11 cases). After submaximal exercise for eight minutes the reduction was from 18% to 10% (double-blind crossover study in 28 cases). It is concluded that disodium cromoglycate partly inhibits the increase of airways resistance after exercise in asthmatic patients.