Transplant of SARS-CoV-2–infected Living Donor Liver: Case Report. Issue 8 (August 2021)

• Record Type: Journal Article
• Authors: Nguyen, Michelle C.; Lee, Eliza J.; Avery, Robin K.; Dioverti-Prono, M. Veronica; Shoham, Shmuel; Tobian, Aaron A. R.; Bloch, Evan M.; Gurakar, Ahmet; Rizkalla, Nicole A.; Cameron, Andrew M.; King, Elizabeth A.; Ottmann, Shane; Garonzik-Wang, Jacqueline M.; Wesson, Russel N.; Philosophe, Benjamin
• Is Part Of: Transplantation direct. Volume 7:Issue 8(2021)
• Publication Date: 2021-08
• Subjects: Transplantation of organs, tissues, etc -- Periodicals; Transplantation -- Periodicals; 362.19795
• DOI: 10.1097/TXD.0000000000001178
• Languages: English
• ISSNs: 2373-8731

Abstract

Abstract : Given the high community prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), transplant programs will encounter SARS-CoV-2 infections in living donors or recipients in the perioperative period. There is limited data on SARS-CoV-2 viremia and organotropism beyond the respiratory tract to inform the risk of transplant transmission of SARS-CoV-2. We report a case of a living donor liver transplant recipient who received a right lobe graft from a living donor with symptomatic PCR-confirmed SARS-CoV-2 infection 3 d following donation. The donor was successfully treated with remdesivir, dexamethasone, and coronavirus disease 2019 (COVID-19) convalescent plasma. No viral transmission was identified, and both donor and recipient had excellent postoperative outcomes. Abstract : Supplemental Digital Content is available in the text.