Rapid self-healing and self-adhesive chitosan-based hydrogels by host-guest interaction and dynamic covalent bond as flexible sensor. (1st December 2021)

• Record Type: Journal Article
• Authors: Ren, Zhijun; Ke, Tao; Ling, Qiangjun; Zhao, Li; Gu, Haibin
• Is Part Of: Carbohydrate polymers. Volume 273(2021)
• Publication Date: 2021-12-01
• Subjects: Conductive hydrogel -- Chitosan -- Poly(vinyl alcohol) -- Host-guest interactions -- Self-healing -- Self-adhesiveness -- Flexible strain sensor; Polysaccharides -- Periodicals; Polysaccharides -- Periodicals; Polysaccharides -- Périodiques; Electronic journals; 547.78
• DOI: 10.1016/j.carbpol.2021.118533
• Languages: English
• ISSNs: 0144-8617

Abstract

Abstract: A sensor used to monitor tissue deformation requires good flexibility, stretchability, self-adhesion, cyto-compatibility, and antibacterial property. Here, we prepared hydrogel sensor based on O -carboxymethyl chitosan (O-CMCS) and poly(vinyl alcohol) (PVA) for monitoring human and organ motions. Based on the host-guest complexing of poly(β-cyclodextrin) with diamantane, a cross-linker containing multiple aldehyde groups was prepared for cross-linking with O-CMCS through Schiff base linkages. Borax was used as the second cross-linker to cross-link PVA through dynamic borate ester bonds. Carbon nanotubes (CNTs) were added into the hydrogels to improve their electrical conductivity and mechanical properties. The obtained hydrogel exhibited rapid self-healing ability with healing efficiency as high as 97%–103% (in 15 s), good adhesion to human skin and wet organ, good antibacterial property, cyto-compatibility, and stretchability. Furthermore, the hydrogel sensor can monitor the respiratory movement of porcine lungs and the beating of rat hearts. Highlights: Supramolecular polyaldehyde cross-linker PCD-CHO was prepared based on the host-guest interaction. Chitosan-based hydrogel was prepared via multiple dynamic crosslinking. Hydrogel shows good self-healing, biocompatible, antibacterial and stretchable properties. Hydrogel possesses good adhesion to tissue or wet tissue. Hydrogel sensor may track heart beats in rats and the respiratory movement of a pig lung in vitro.