Microarrays—Solutions to the Protein Challenge. (January 2005)

• Record Type: Journal Article
• Authors: Clarke, Jeremy
• Is Part Of: Biotechniques. Volume 38:Number 1(2005)
• Page Start: 149
• Page End: 151
• Publication Date: 2005-01
• Subjects: Biology, Experimental -- Periodicals; Molecular biology -- Periodicals; Medical technology -- Periodicals; Biology, Experimental; Medical technology; Molecular biology; Clinical Laboratory Techniques -- Periodicals; Research -- Periodicals; Medical Laboratory Science -- Periodicals; Periodicals; Electronic journals; 570
• DOI: 10.2144/05381AF02
• Languages: English
• ISSNs: 0736-6205

Abstract

The study of the proteome presents many challenges to the researcher. One of these is finding the best way to study tens of thousands of proteins in as short a time as possible. With the advances in miniaturization and automation over the recent past, several approaches are now available for producing high-density protein arrays on custom slides. After the arraying process is complete, lessons learned in the automated hybridization and imaging of cDNA and oligonucleotides now allow the consistent high-throughput study of antibody/antigen interactions.