Effects of heavy metals on reproduction owing to infertility. Issue 8 (29th May 2021)

• Record Type: Journal Article
• Authors: Bhardwaj, Jitender K.; Paliwal, Aakansha; Saraf, Priyanka
• Is Part Of: Journal of biochemical and molecular toxicology. Volume 35:Issue 8(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-05-29
• Subjects: apoptosis -- heavy metal -- infertility -- oxidative stress -- reactive oxygen species -- toxicity; Biochemistry -- Periodicals; Molecular biology -- Periodicals; Toxicology -- Periodicals; 574
• DOI: 10.1002/jbt.22823
• Languages: English
• ISSNs: 1095-6670

Abstract

Abstract: The reproductive performance of most of the species is adversely affected by hazardous heavy metals like lead, cadmium, mercury, arsenic, zinc, and copper. Heavy metals are liberated in the environment by natural sources like rock weathering, volcanic eruption, and other human activities like industrial discharge, mineral mining, automobile exhaust, and so forth. Heavy metals alter several reproductive functions in both males and females like a decrease in sperm count, motility, viability, spermatogenesis, hormonal imbalance, follicular atresia, and delay in oocyte maturation, and so forth, and thus, forms an important aspect of reproductive toxicology. The present review compiles toxicity aspects of various heavy metals and their efficacy and mechanism of action in mammals. Abstract :