Letter to the editor: radiomics analysis for predicting pembrolizumab response in patients with advanced rare cancers. Issue 7 (27th July 2021)

• Record Type: Journal Article
• Authors: Cunha, Mateus Trinconi; Carvalho, Vinicius Jardim; Loureiro, Rafael Maffei; Brantis-de-Carvalho, Carlos Eduardo; Cintra, Murilo Bicudo; de Castro Junior, Gilberto
• Is Part Of: Journal for immunotherapy of cancer. Volume 9:Issue 7(2021)
• Publication Date: 2021-07-27
• Subjects: immunotherapy; Cancer -- Immunotherapy -- Periodicals; Cancer -- Immunological aspects -- Periodicals; Tumors -- Immunological aspects -- Periodicals; Immunotherapy -- Periodicals; 616.99406105
• DOI: 10.1136/jitc-2021-003044
• Languages: English
• ISSNs: 2051-1426

Abstract

Abstract : A commentary on the original research article: 'Radiomics analysis for predicting pembrolizumab response in patients with advanced rare cancers'. Of note, the predictor selection process, the cross-validation method, along with the lack of final testing of the developed model with a separated data set may mask overfitting, overestimating performance metrics.