Actigraphy-recorded sleep efficiency and hippocampal volume are related to visual and verbal rate of forgetting in older adults. Issue 6 (2nd November 2021)

• Record Type: Journal Article
• Authors: Lee, Alessandra; Lah, Suncica; Joplin, Samantha; Haroutonian, Carla; Pye, Jonathon; Mowszowski, Loren; Duffy, Shantel L.; Naismith, Sharon L.
• Is Part Of: Aging, neuropsychology, and cognition. Volume 28:Issue 6(2021)
• Page Start: 936
• Page End: 958
• Publication Date: 2021-11-02
• Subjects: Dementia -- accelerated long-term forgetting -- MCI -- SMC -- hippocampus -- sleep; Aging -- Periodicals; Cognition in old age -- Periodicals; Cognition disorders in old age -- Periodicals; Neuropsychology -- Periodicals; Aging -- periodicals; Neuropsychology -- periodicals; Cognition -- periodicals; Mental Disorders -- periodicals; Gerontology -- periodicals; Mental Health -- periodicals; 155.67
• DOI: 10.1080/13825585.2020.1842849
• Languages: English
• ISSNs: 1382-5585

Abstract

ABSTRACT: This study aimed to determine if older adults "at-risk" for dementia (those with MCI or SMC) exhibit accelerated long-term forgetting (ALF) and whether rate of forgetting (RoF) is associated with sleep efficiency, hippocampal volume and demographic/clinical features. Forty-nine "at-risk" participants and eighteen controls underwent examination. Memory was assessed using the Scene Memory Task (SMT) and WMS-III Logical Memory (LM) subtest. Tests were administered at baseline, 24 hours and 2 weeks. While our study did not find ALF in those "at-risk" for dementia, on the SMT, RoF over 24 hours and 2 weeks was negatively correlated with sleep efficiency. For LM, RoF at 2 weeks was moderately associated with left hippocampal volume. Neither visual or verbal RoF was correlated with demographic or clinical variables (age, MMSE, IQ, GDS-15). While ALF was not observed in this sample, our results suggest that visual and verbal forgetting have differential predictors.