Abnormal blood viscosity and haemostasis in long-standing retinal vein occlusion. Issue 3 (March 1983)

• Record Type: Journal Article
• Authors: Trope, G E; Lowe, G D; McArdle, B M; Douglas, J T; Forbes, C D; Prentice, C M; Foulds, W S
• Is Part Of: British journal of ophthalmology. Volume 67:Issue 3(1983)
• Page Start: 137
• Page End: 142
• Publication Date: 1983-03
• Subjects: Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.67.3.137
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : Blood viscosity and several haemostatic factors were measured in 42 patients with long-standing retinal vein occlusion and 33 control subjects. Blood viscosity, haematocrit, plasma viscosity, fibrinogen, fibrinopeptide A, and beta-thromboglobulin were increased in the 20 subjects with capillary nonperfusion or new vessels, but not in the 22 subjects without these complications. Patients with nonperfusion or new vessels also had a lower platelet count than patients without complications. Increased levels of factor VIII antigen and decreased levels of antithrombin III were found in the retinal vein occlusion group as a whole. These findings suggest that blood viscosity, platelets, and coagulation may be involved in retinal vein occlusion and its vascular complications.