Prevention of torsade de pointes in the congenital long QT syndrome: use of a pause prevention pacing algorithm. Issue 4 (1st April 1998)

• Record Type: Journal Article
• Authors: Viskin, S; Fish, R; Roth, A; Copperman, Y
• Is Part Of: Heart. Volume 79:Issue 4(1998)
• Page Start: 417
• Page End: 419
• Publication Date: 1998-04-01
• Subjects: long QT syndrome -- torsade de pointes -- ventricular fibrillation -- ventricular tachycardia -- pacing; Heart -- Diseases -- Treatment -- Periodicals; Cardiology -- Periodicals; 616.12
• DOI: 10.1136/hrt.79.4.417
• Languages: English
• ISSNs: 1355-6037

Abstract

Abstract : Torsade de pointes in the congenital long QT syndrome (LQTS) is often pause dependent. Thus, the main goal of pacemaker treatment in the LQTS may be the prevention of pauses that facilitate the onset of torsade de pointes. A pause prevention pacing algorithm (rate smoothing) was used for arrhythmia prevention in a 14 year old girl with congenital LQTS. By temporarily increasing the pacing rate after spontaneous premature beats, rate smoothing down of 18% prevented postextrasystolic pauses, pause related T-U changes, and recurrence of pause induced torsade de pointes. Rate smoothing is a potentially useful tool that ought to be evaluated for the prevention of torsade de pointes in the LQTS.