HER2 testing in the UK: recommendations for breast and gastric in-situ hybridisation methods. Issue 8 (20th June 2011)

• Record Type: Journal Article
• Authors: Bartlett, J M S; Starczynski, J; Atkey, Neil; Kay, E; O'Grady, A; Gandy, Michael; Ibrahim, Merdol; Jasani, Bharat; Ellis, I O; Pinder, S E; Walker, R A
• Is Part Of: Journal of clinical pathology. Volume 64:Issue 8(2011)
• Page Start: 649
• Page End: 653
• Publication Date: 2011-06-20
• Subjects: Breast pathology -- CERB 2 -- fish; Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.2011.089847
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : These guidelines supplement existing guidelines on HER2 testing by immunohistochemistry and in-situ hybridisation(ISH) methods in the UK. They provide a specific focus on aspects of guidance relevant to HER2 ISH testing methods, both fluorescent and chromogenic. They are formulated to give advice on methodology, interpretation and quality control for ISH-based testing of HER2 status in common tumour types, including both breast and gastric tumours. The aim is to ensure that all ISH-based testing is accurate, reliable and timely.