Comparison of Laparoscopy and Laparotomy for Management of Endometrial Carcinoma: A Meta-analysis. Issue 3 (1st March 2009)

• Record Type: Journal Article
• Authors: Ju, Woong; Myung, Seung-Kwon; Kim, Yeol; Choi, Hyuck Jae; Kim, Seung Cheol
• Is Part Of: International journal of gynecological cancer. Volume 19:Issue 3(2009)
• Page Start: 400
• Page End: 406
• Publication Date: 2009-03-01
• Subjects: Meta-analysis -- Laparoscopy -- Laparotomy -- Endometrial cancer; Generative organs, Female -- Cancer -- Periodicals; 616.99465
• DOI: 10.1111/IGC.0b013e3181a1caf8
• Languages: English
• ISSNs: 1048-891X

Abstract

Abstract : Background: This meta-analysis was performed to investigate the outcome of laparoscopic surgery for endometrial carcinoma compared with laparotomy. Methods: We searched the MEDLINE (PubMed), EMBASE, and Cochrane Review databases in September 2007. Three independent evaluators selected the articles according to predetermined selection criteria. Results: Thirteen comparative studies (5 prospective and 8 retrospective) that met the selection criteria were included. In a fixed-effects meta-analysis, the overall survival and therecurrence rate showed no significant differences between the laparoscopy and the laparotomy groups, with odds ratios of 0.84 (95% confidence interval, 0.64-1.62) and 0.90 (95% confidence interval, 0.49-1.16), respectively. However, the complication rate was lower in the laparoscopy group than in the laparotomy group with an odds ratio of 0.43 (95% confidence interval, 0.32-0.58). Conclusions: The survival outcome and recurrence rate after laparoscopic surgery for endometrial carcinoma were similar to those in the laparotomy procedures. However, the complication rate was lower after laparoscopy compared with laparotomy.