Multimodal imaging reveals the role of γ activity in eating-reflex seizures. Issue 10 (19th November 2010)

• Record Type: Journal Article
• Authors: Blauwblomme, Thomas; Kahane, Philippe; Minotti, Lorella; Grouiller, Frédéric; Krainik, Alexandre; Vercueil, Laurent; Chabardès, Stéphan; Hoffmann, Dominique; David, Olivier
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 82:Issue 10(2011)
• Page Start: 1171
• Page End: 1173
• Publication Date: 2010-11-19
• Subjects: Case report -- eating seizures -- functional MRI -- gamma oscillations -- gustatory cortex -- insula -- reflex epilepsy -- stereo-electroencephalography -- brain mapping -- EEG -- epilepsy -- surgery; Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.2010.212696
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : In reflex epilepsies, alteration of γ oscillations may mediate transition between interictal and ictal states. Here, we explored a patient having seizures triggered by syrup intake. From intracranial electroencephalography combined with functional MRI, the overlap of the gustatory cortex and of the preictal and ictal onset zones, as defined by early gamma changes, motivated the successful resective surgery of the middle short gyrus of the right insula. This case provides a rare demonstration from human gamma activity that the route to seizure may be supported by the interplay between physiological and epileptogenic networks.