Eye movements in amyotrophic lateral sclerosis and its mimics: a review with illustrative cases. Issue 1 (19th November 2010)

• Record Type: Journal Article
• Authors: Donaghy, Colette; Thurtell, Matthew J; Pioro, Erik P; Gibson, J Mark; Leigh, R John
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 82:Issue 1(2011)
• Page Start: 110
• Page End: 116
• Publication Date: 2010-11-19
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.2010.212407
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : Abnormal eye movements are increasingly recognised in patients with amyotrophic lateral sclerosis (ALS) and, when they occur, may provide insights into the pattern and pathogenesis of the disease process. In patients with disorders that mimic ALS, abnormal eye movements may point to the correct diagnosis. In both of these circumstances, systematic examination of eye movements and interpretation of the findings with reference to modern concepts of their neural substrate will aid diagnosis and suggest pathogenesis. Here, key points with illustrative case histories and eye movement records are highlighted.