Susceptibility vessel sign on MRI predicts better clinical outcome in patients with anterior circulation acute stroke treated with stent retriever as first-line strategy. (28th August 2018)

• Record Type: Journal Article
• Authors: Bourcier, Romain; Hassen, Wagih Ben; Soize, Sébastien; Roux, Pascal; Labreuche, Julien; Kyheng, Maeva; Tisserand, Marie; Rosso, Charlotte; Blanc, Raphael; Piotin, Michel; Derraz, Imad; Boulouis, Gregoire; Oppenheim, Catherine; Desal, Hubert; Bracard, Serge; Lapergue, Bertrand; Naggara, Olivier
• Other Names: author non-byline.; M Piotin author non-byline.; R Blanc author non-byline.; H Redjem author non-byline.; G Ciccio author non-byline.; S Smajda author non-byline.; M Mazighi author non-byline.; R Fahed author non-byline.; Jp Desilles author non-byline.; B Lapergue author non-byline.; G Rodesch author non-byline.; A Consoli author non-byline.; O Coskun author non-byline.; F Di Maria author non-byline.; F Bourdain author non-byline.; Jp Decroix author non-byline.; A Wang author non-byline.; M Tchikviladze author non-byline.; S Evrard author non-byline.; F Turjman author non-byline.; B Gory author non-byline.; Pe Labeyrie author non-byline.; R Riva author non-byline.; C Mounayer author non-byline.; S Saleme author non-byline.; V Costalat author non-byline.; A BonafÈ author non-byline.; O Eker author non-byline.; G Gascou author non-byline.; C Dargazanli author non-byline.; S Bracard author non-byline.; R Tonnelet author non-byline.; Al Derelle author non-byline.; R Anxionnat author non-byline.; H Desal author non-byline.; R Bourcier author non-byline.; B Daumas-duport author non-byline.; J Berge author non-byline.; X Barreau author non-byline.; G Margnat author non-byline.; L Djemmane author non-byline.; J Labreuche author non-byline.; A Duhamel author non-byline.; bonafÈ alain author non-byline.; Leclerc Xavier author non-byline.; Agrinier Nelly author non-byline.; Bakchine Serge author non-byline.; Baronnet Flore author non-byline.; Beaumont Marine author non-byline.; Bejot Yannick author non-byline.; Berge Jerome author non-byline.; Bintner Marc author non-byline.; Bourcier Romain author non-byline.; Cho Tae Hee author non-byline.; Clarencon FrÈdÈric author non-byline.; Cogez Julien author non-byline.; Cordonnier Charlotte author non-byline.; Denier Christian author non-byline.; Derelle Anne Laure author non-byline.; Detante Olivier author non-byline.; Faivre Anthony author non-byline.; Ferrier Anne author non-byline.; Gimenez Laetitia author non-byline.; Godard Sophie author non-byline.; Guillon Benoit author non-byline.; Houdart Emmanuel author non-byline.; Lapergue Bertrand author non-byline.; Musacchio Mariano author non-byline.; Naggara Olivier author non-byline.; Neau Jean Philippe author non-byline.; Obadia Michael author non-byline.; Pasco-papon Anne author non-byline.; Piotin Michel author non-byline.; Pierot Laurent author non-byline.; Raoult Helene author non-byline.; Richard SÈbastien author non-byline.; Ricolfi Frederic author non-byline.; Ronziere Thomas author non-byline.; Saliou Guillaume author non-byline.; Sibon Igor author non-byline.; Soize Sebastien author non-byline.; Sedat Jacques author non-byline.; Stapf Christian author non-byline.; Suissa Laurent author non-byline.; Tisserand Marie author non-byline.; Turjman Francis author non-byline.; Velasco) Stephane author non-byline.; Trial investigators are alain bonafÈ (de partment of neuroradiology The Thrace author non-byline.; Chauliac hospital Gui De author non-byline.; Montpellier author non-byline.; France) author non-byline.; (department of radiology Xavier Leclerc author non-byline.; Of lille University Hospital author non-byline.; Lille author non-byline.; France) author non-byline.; (department of clinical epidemiology inserm cic-ec 1433 Nelly Agrinier author non-byline.; Lorraine and university hospital of nancy University Of author non-byline.; Nancy author non-byline.; France) author non-byline.; (department of neurology Serge Bakchine author non-byline.; Of reims University Hospital author non-byline.; Reims author non-byline.; France) author non-byline.; (stroke unit Flore Baronnet author non-byline.; Group and paris 6 universityópierre et marie curie PitiÈ-salpÍtriËre Hospital author non-byline.; Paris author non-byline.; France) author non-byline.; (department of inserm cic-it Marine Beaumont author non-byline.; Lorraine and university hospital of nancy University Of author non-byline.; Nancy author non-byline.; France) author non-byline.; (department of neurology Yannick Bejot author non-byline.; Of dijon University Hospital author non-byline.; Dijon author non-byline.; France) author non-byline.; (department of interventional and diagnostic neuroradiology Jerome Berge author non-byline.; Of bordeaux University Hospital author non-byline.; Bordeaux author non-byline.; France) author non-byline.; (department of neuroradiology sud-reunion hospital group Marc Bintner author non-byline.; Pierre Saint author non-byline.; France) author non-byline.; (department of interventional and diagnostic neuroradiology Romain Bourcier author non-byline.; Of nantes University Hospital author non-byline.; Nantes author non-byline.; France) author non-byline.; Cho (department of neurology Tae Hee author non-byline.; Of lyon University Hospital author non-byline.; Lyon author non-byline.; France) author non-byline.; (department of interventional neuroradiology pitiÈ-salpÍtriËre hospital group and paris 6 universityópierre et marie curie FrÈdÈric Clarencon author non-byline.; Paris author non-byline.; France) author non-byline.; (department of neurology Julien Cogez author non-byline.; Of caen University Hospital author non-byline.; Caen author non-byline.; France) author non-byline.; (department of neurology Charlotte Cordonnier author non-byline.; Of lille University Hospital author non-byline.; Lille author non-byline.; France) author non-byline.; (department of neurology Christian Denier author non-byline.; Of bicÍtre University Hospital author non-byline.; Kremlin-bicÍtre Le author non-byline.; France) author non-byline.; Derelle (department of diagnostic and interventional neuroradiology Anne Laure author non-byline.; Of nancy University Hospital author non-byline.; Nancy author non-byline.; France) author non-byline.; (department of neurology Olivier Detante author non-byline.; Of grenoble University Hospital author non-byline.; Grenoble author non-byline.; France) author non-byline.; (department of neurology Anthony Faivre author non-byline.; Des armÈes HÙpital Díinstruction author non-byline.; Anne Sainte author non-byline.; Toulon author non-byline.; France) author non-byline.; Ferrier Anne author non-byline.; Neurology (department Of author non-byline.; Gabriel-montpied University Hospital author non-byline.; Clermont-Ferrand author non-byline.; France) author non-byline.; (department of neurology Laetitia Gimenez author non-byline.; Of limoges University Hospital author non-byline.; Limoges author non-byline.; France) author non-byline.; (department of neurology Sophie Godard author non-byline.; Of angers University Hospital author non-byline.; Angers author non-byline.; France) author non-byline.; (department of neurology Benoit Guillon author non-byline.; Of nantes University Hospital author non-byline.; Nantes author non-byline.; France) author non-byline.; (department of neuroradiology Emmanuel Houdart author non-byline.; LariboisiËre University Hospital author non-byline.; Paris author non-byline.; France) author non-byline.; (department of neurology Bertrand Lapergue author non-byline.; Hospital Foch author non-byline.; Suresnes author non-byline.; France) author non-byline.; (department of neuroradiology Mariano Musacchio author non-byline.; Hospital Pasteur author non-byline.; Colmar author non-byline.; France) author non-byline.; (department of neuroradiology Olivier Naggara author non-byline.; And paris-descartes university Sainte-anne Hospital author non-byline.; U894 Inserm author non-byline.; Paris author non-byline.; France) author non-byline.; Neau (department of neurology Jean Philippe author non-byline.; Of poitiers University Hospital author non-byline.; Poitiers author non-byline.; France) author non-byline.; (department of neurology Michael Obadia author non-byline.; Foundation Rothschild Ophthalmological author non-byline.; Paris author non-byline.; France) author non-byline.; (department of radiology Anne Pasco-papon author non-byline.; Of angers University Hospital author non-byline.; Angers author non-byline.; France) author non-byline.; (department of interventional neuroradiology [mp] rothschild ophthalmological foundation Michel Piotin author non-byline.; Paris author non-byline.; France) author non-byline.; (department of neuroradiology Laurent Pierot author non-byline.; Of reims University Hospital author non-byline.; Reims author non-byline.; France) author non-byline.; (department of neuroradiology Helene Raoult author non-byline.; Of rennes University Hospital author non-byline.; Rennes author non-byline.; France) author non-byline.; (department of neurology university hospital of nancy SÈbastien Richard author non-byline.; Nancy author non-byline.; France) author non-byline.; (department of neuroradiology Frederic Ricolfi author non-byline.; Of dijon University Hospital author non-byline.; Dijon author non-byline.; France) author non-byline.; (department of neurology Thomas Ronziere author non-byline.; Of rennes University Hospital author non-byline.; Rennes author non-byline.; France) author non-byline.; (department of neuroradiology Guillaume Saliou author non-byline.; Of bicÍtre University Hospital author non-byline.; Kremlin-bicÍtre Le author non-byline.; France) author non-byline.; (department of neurology Igor Sibon author non-byline.; Of bordeaux University Hospital author non-byline.; Bordeaux author non-byline.; France) author non-byline.; (department of neuroradiology Sebastien Soize author non-byline.; Of reims University Hospital author non-byline.; Reims author non-byline.; France) author non-byline.; (department of radiology Jacques Sedat author non-byline.; Of nice University Hospital author non-byline.; Nice author non-byline.; France) author non-byline.; (department of neurology Christian Stapf author non-byline.; LariboisiËre University Hospital author non-byline.; Paris author non-byline.; France) author non-byline.; (department of neurology Laurent Suissa author non-byline.; Of nice University Hospital author non-byline.; Nice author non-byline.; France) author non-byline.; (department of neuroradiology Marie Tisserand author non-byline.; And paris- descartes university Sainte-anne Hospital author non-byline.; U894 Inserm author non-byline.; Paris author non-byline.; France) author non-byline.; (department of interventional neuroradiology Francis Turjman author non-byline.; Of lyon University Hospital author non-byline.; Lyon author non-byline.; France) author non-byline.; Velasco (departments of radiology And Stephane author non-byline.; Of poitiers University Hospital author non-byline.; Poitiers author non-byline.; France) author non-byline.;
• Is Part Of: Journal of neurointerventional surgery. Volume 11:Number 4(2019)
• Page Start: 328
• Page End: 333
• Publication Date: 2018-08-28
• Subjects: mri -- stroke -- thrombectomy; Nervous system -- Surgery -- Periodicals; Cerebrovascular disease -- Surgery -- Periodicals; 617.48
• DOI: 10.1136/neurintsurg-2018-014217
• Languages: English
• ISSNs: 1759-8478

Abstract

Abstract : Background: Susceptibility vessel sign (SVS) can be a useful MRI biomarker of an occlusion but its relationship with clinical outcomes of acute ischemic stroke (AIS) is yet to be fully elucidated. Objective: To investigate SVS in relation to the clinical outcomes after mechanical thrombectomy using a stent retriever (SR) as first-line approach in patients with AIS. Material and methods: We included patients with a first-line SR approach for anterior AIS from the the Contact Aspiration vs Stent Retriever for Successful Revascularization (ASTER) and THRombectomie des Artères CErebrales (THRACE) trials when both baseline imaging of SVS and 90-day modified Rankin Scale (mRS) scores were available. Patients were assigned to two groups based on the presence of an SVS (independent core laboratory), and the overall distributions of the mRS score at 90 days (shift analysis) and clinical independence (mRS score ≤2) were compared. Results: 217 patients were included and SVS was diagnosed in 76.0% of cases (n=165, 95% CI 70.4% to 81.7%). After adjustment for potential confounders, SVS+ was significantly associated with 90-day mRS improvement (adjusted common OR=2.75; 95% CI 1.44 to 5.26) and favorable outcome (adjusted common OR=2.76; 95% CI 1.18 to 6.45). Conclusion: Based on results for patients of the ASTER and THRACE trials receiving first-line SR treatment, SVS was associated with lower disability at 3 months. Large prospective studies using MRI-based thrombus evaluation are warranted.