Management of early oral cavity squamous cancers. (May 2020)

• Record Type: Journal Article
• Authors: Chatterjee, Abhishek; Laskar, Sarbani Ghosh; Chaukar, Devendra
• Is Part Of: Oral oncology. Volume 104(2020)
• Publication Date: 2020-05
• Subjects: Oral cancer -- Early -- Management -- Adjuvant therapy -- Risk; Mouth -- Cancer -- Periodicals; Mouth -- Tumors -- Periodicals; Mouth Diseases -- Periodicals; Mouth Neoplasms -- Periodicals; Bouche -- Cancer -- Périodiques; Bouche -- Tumeurs -- Périodiques; Tumeurs -- Périodiques; Electronic journals; 616.9943105
• DOI: 10.1016/j.oraloncology.2020.104627
• Languages: English
• ISSNs: 1368-8375

Abstract

Highlights: Early oral cavity cancers are associated with favorable outcomes. Single modality treatment in the form of surgery with negative margins is the treatment of choice. Surgery should address both the primary and the neck. Depth of Infiltration (DOI) should be consistently reported on routine histopathology as opposed to thickness. Emerging role for adjuvant therapy in the setting of multiple adverse features. Abstract: Early oral cavity cancers comprise a favorable entity, amenable to clinical staging and single modality treatment. Surgery typically forms the mainstay of treatment and should ideally address both the primary and the neck in all cases. Careful attention must be paid to reconstruction and rehabilitation of such patients. Radical radiotherapy mainly in the form of brachytherapy can achieve excellent disease related and functional outcomes in a carefully chosen subset of patients. Increasingly, a subset of patients is being recognized, who harbor single or multiple adverse features on histopathology and may therefore benefit from escalation of adjuvant therapy. This review discusses the management of early oral cavity squamous carcinomas (Early OSCCs) in detail and highlights the dilemmas and controversies faced in the management of the same.