FUNDUS AUTOFLUORESCENCE PATTERNS IN CENTRAL SEROUS CHORIORETINOPATHY. Issue 7 (July 2020)

• Record Type: Journal Article
• Authors: Han, Jisang; Cho, Nam Suk; Kim, Kiyoung; Kim, Eung Suk; Kim, Do Gyun; Kim, Joon Mo; Yu, Seung-Young
• Is Part Of: Retina. Volume 40:Issue 7(2020)
• Publication Date: 2020-07
• Subjects: autofluorescence -- central serous chorioretinopathy -- classification -- optical coherence tomography; Retina -- Diseases -- Periodicals; Retinal Diseases; Vitreous Body; 617.735
• DOI: 10.1097/IAE.0000000000002580
• Languages: English
• ISSNs: 0275-004X

Abstract

Abstract : Purpose: To investigate the patterns of fundus autofluorescence (FAF) abnormalities in patients with central serous chorioretinopathy (CSC). Methods: This cross-sectional observational study included 126 eyes of 118 patients who were diagnosed with central serous chorioretinopathy from December 2006 to April 2012 at Kyung Hee University Hospital, Seoul, Korea. Fundus autofluorescence patterns were analyzed with spectral domain optical coherence tomography and visual acuity. Results: Fundus autofluorescence patterns were grouped as blocked (38.9%), mottled (8.7%), hyper (31.0%), hyper/hypo (13.5%), or descending tract (8.0%). The duration of symptoms was 7.8 (±20.4), 28.3 (±31.8), 42.5 (±69.1), 163.8 (±183.5), and 174.5 (±162.3) days in the blocked, mottled, hyper, descending tract, and hyper/hypo groups, respectively ( P < 0.001). The blocked FAF group had the best visual acuity ( P = 0.011). The intact ellipsoid zone on the spectral domain optical coherence tomography was mostly found in the blocked FAF group ( P < 0.001), and the disrupted ellipsoid zone was commonly exhibited in the hyper/hypo and descending tract groups. Disrupted external limiting membrane line on the spectral domain optical coherence tomography was seen in two patients of the descending tract group only. Conclusion: The FAF abnormalities in central serous chorioretinopathy show multiple patterns and are related with the chronicity and visual acuity. Fundus autofluorescence patterns in central serous chorioretinopathy are helpful when considering the timing of treatment and predicting the disease status. Abstract : The fundus autofluorescence pattern of central serous chorioretinopathy is related to the disease chronicity, visual acuity, and optical coherence tomography findings. Classification of fundus autofluorescence patterns in central serous chorioretinopathy is helpful when predicting the disease status and considering the timing of treatment.