HLA-B27 frequency in Greek patients with acute anterior uveitis. Issue 11 (November 1977)

• Record Type: Journal Article
• Authors: Zervas, J; Tsokos, G; Papadakis, G; Kabouklis, E; Papadopoulos, D
• Is Part Of: British journal of ophthalmology. Volume 61:Issue 11(1977)
• Page Start: 699
• Page End: 701
• Publication Date: 1977-11
• Subjects: Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.61.11.699
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : The histocompatibility antigen HLA-B27 was identified in 12 out of 33 patients with acute non-granulomatous anterior uveitis. This is a frequency of 36.36%, compared with 4.72% in controls. Seven patients had in addition evidence of systemic disease, including ankylosing spondylitis, sacroiliitis, Reiter's disease, Still's disease, and rheumatoid arthritis. Five of these were HLA-B27 positive, which suggests that the uveitis in many of these cases has a similar aetiology to the uveitis in those with rheumatic disease. It appears that the more severe cases of acute anterior uveitis are related more frequently to the presence of HLA-B27.