The late effects of fetal growth patterns. Issue 4 (21st June 2006)

• Record Type: Journal Article
• Authors: Bloomfield, F H; Oliver, M H; Harding, J E
• Is Part Of: Archives of disease in childhood. Volume 91:Issue 4(2006)
• Page Start: F299
• Page End: F304
• Publication Date: 2006-06-21
• Subjects: IGF, insulin-like growth factor -- PI, ponderal index; birth weight -- twins -- nutrition -- developmental origins of health and disease -- periconceptional nutrition; Infants -- Diseases -- Periodicals; Newborn infants -- Diseases -- Periodicals; Fetus -- Diseases -- Periodicals; 618.920105
• DOI: 10.1136/adc.2005.076646
• Languages: English
• ISSNs: 1359-2998

Abstract

Abstract : The immediate prenatal and postnatal consequences of reduced fetal growth have long been known. The longer term associations between reduced birth weight and adult disease risk are also now well established. Reduced fetal growth is usually detected late in gestation, and the assumption has been that this is the time when factors regulating fetal growth have their greatest effect. However, recent evidence suggests that both the growth trajectory of the fetus and its adaptive responses to the prenatal and postnatal environment may be determined in the period around the time of conception.