Long term effects of long chain polyunsaturated fats in hyperphenylalaninemic children. Issue 7 (1st July 2003)

• Record Type: Journal Article
• Authors: Agostoni, C; Verduci, E; Massetto, N; Fiori, L; Radaelli, G; Riva, E; Giovannini, M
• Is Part Of: Archives of disease in childhood. Volume 88:Issue 7(2003)
• Page Start: 582
• Page End: 583
• Publication Date: 2003-07-01
• Subjects: diet -- docosahexaenoic acid -- hyperphenylalaninemic -- long chain polyunsaturated fatty acids; CE, cholesterol esters -- DHA, docosahexaenoic acid -- Ery, erythrocyte total lipids -- EryPE, phosphatidylethanolamine -- HPA, hyperphenylalaninemic -- LCPUFA, long chain polyunsaturated fatty acids -- Phe, phenylalanine -- PL, phospholipids -- TG, triglycerides -- TL, total lipids -- VEP, visual evoked potential; Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.88.7.582
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : Blood fatty acid status and visual function of 20 treated hyperphenylalaninemic (HPA) children, randomly allocated into two groups to receive supplementation of either long chain polyunsaturated fatty acids (LCPUFA), including docosahexaenoic acid (DHA), or placebo for 12 months, have been investigated three years after the end of the treatment. Although in the LCPUFA group blood DHA levels and P100 wave latency improved at the end of supplementation, they had returned to baseline after three years.