Negative symptoms in first episode schizophrenia: Results from the "parma early psychosis" program. (13th April 2021)

• Record Type: Journal Article
• Authors: Pelizza, L.; Leuci, E.; Maestri, D.; Quattrone, E.; Paulillo, G.; Pellegrini, P.; Azzali, S.
• Is Part Of: European psychiatry. Volume 64:Supplement 1(2021)
• Page Start: S168
• Page End: S169
• Publication Date: 2021-04-13
• Subjects: psychopathology -- negative symptoms -- schizophrénia -- early psychosis; Psychiatry -- Periodicals; Mental illness -- Periodicals; Electronic journals; 616.89
• DOI: 10.1192/j.eurpsy.2021.448
• Languages: English
• ISSNs: 0924-9338

Abstract

Abstract : Introduction: Identifying distinct dimensions of negative symptoms in First Episode Schizophrenia (FES) might result in a better understanding and treatment of this invalidating symptomatology. Objectives: Aim of this study was to examine negative symptom structure in FES patients using the Positive and Negative Syndrome Scale (PANSS). Methods: All 147 participants, aged 12–35 years, completed the PANSS and the Global Assessment of Functioning (GAF) scale. A principal component analysis with varimax rotation was performed to investigate PANSS negative symptom structure in the FES total sample. Results: A 2-factor model (i.e. "Expressive Deficits" and "Asociality" dimensions) was identified. Only "Expressive Deficits" domain had a significant negative correlation with baseline GAF score. Conclusions: This bipartite solution seems to be adequate to describe the phenomenological variety of negative symptoms experienced by FES individuals at the point of entry in early intervention services. Disclosure: No significant relationships.