Chronic myeloid leukaemia occurring in a patient with hairy cell leukaemia. Issue 12 (1st December 2000)

• Record Type: Journal Article
• Authors: Wandroo, F A; Bareford, D; El-Jehani, F
• Is Part Of: Journal of clinical pathology. Volume 53:Issue 12(2000)
• Page Start: 940
• Page End: 941
• Publication Date: 2000-12-01
• Subjects: hairy cell leukaemia -- chronic myeloid leukaemia -- acute lymphoblastic leukaemia; Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.53.12.940
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : Occurrences of second malignancies in hairy cell leukaemia are well recognised. Most of these malignancies are either solid tumours or lymphoproliferative disorders. The association of myeloproliferative disorders with hairy cell leukaemia (HCL) is very rare. This report describes a case of a patient with HCL who after remaining in remission developed Philadelphia chromosome positive chronic myeloid leukaemia (CML), which rapidly transformed to acute lymphoblastic leukaemia with further cytogenetic abnormalities.