Effect of body temperature on visual evoked potential delay and visual perception in multiple sclerosis. Issue 11 (November 1977)

• Record Type: Journal Article
• Authors: Regan, D; Murray, T J; Silver, R
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 40:Issue 11(1977)
• Page Start: 1083
• Page End: 1091
• Publication Date: 1977-11
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.40.11.1083
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : Seven multiple sclerosis patients were cooled and four heated, but evoked potential delay changed in only five out 11 experiments. Control limits were set by cooling eight and heating four control subjects. One patient gave anomalous results in that although heating degraded perceptual delay and visual acuity, and depressed the sine wave grating MTF, double-flash resolution was improved. An explanation is proposed in terms of the pattern of axonal demyelination. The medium frequency flicker evoked potential test seems to be a less reliable means of monitoring the progress of demyelination in multiple sclerosis patients than is double-flash campimetry or perceptual delay campimetry, although in some situations the objectivity of the evoked potential test would be advantageous.