Endocrine and Metabolic Disorders in Bronchial Carcinoma. Issue 5734 (28th November 1970)

• Record Type: Journal Article
• Authors: Azzopardi, J. G.; Freeman, E.; Poole, G.
• Is Part Of: BMJ. Volume 4:Issue 5734(1970)
• Page Start: 528
• Page End: 529
• Publication Date: 1970-11-28
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.4.5734.528
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : In an unselected series of 185 patients with histologically confirmed bronchial carcinoma 16 had endocrine disturbances attributable to the tumour (excluding pulmonary osteoarthropathy). Of these, 11 patients had hypercalcaemia; three inappropriate secretion of antidiuretic hormone; one Cushing's disease; three hypertrophic osteoarthropathy; and one gynaecomastia. Cushing's disease and inappropriate antidiuresis are specifically associated with oat-cell tumours, and hypercalcaemia occurs most frequently with squamous carcinoma. A negative correlation exists between gynaecomastia and osteoarthropathy on the one hand and oat-cell carcinoma on the other.