Hypertrophic Herpes Simplex With Subsequent Development of Plasma Cell Vulvitis: A Potential Diagnostic Pitfall. (March 2020)

• Record Type: Journal Article
• Authors: Elghobashy, Maiar; Elgaly, Maher; Salmons, Nabeel; El-Ghobashy, Alaa
• Is Part Of: International journal of gynecological pathology. Volume 39:Number 2(2020)
• Publication Date: 2020-03
• Subjects: Herpes genitalis -- HIV -- Herpes simplex -- HSV -- Plasma cell vulvitis; Gynecologic pathology -- Periodicals; Gynecology -- Periodicals; Generative organs, Female -- Diseases -- Periodicals; 618.10705
• DOI: 10.1097/PGP.0000000000000599
• Languages: English
• ISSNs: 0277-1691

Abstract

Abstract : A 37-yr-old patient previously diagnosed with human immunodeficiency virus initially presented with a genital lesion which upon histologic assessment was diagnosed as a pseudotumor associated with herpes simplex virus infection. The pseudotumor responded to initial treatment with Acyclovir, however, the lesion recurred 2 yr later and was diagnosed as plasma cell vulvitis. We discuss the clinical presentation, diagnostic work up and treatment options of such a rare lesion.