Magnetization transfer and frequency distribution effects in the SSFP ellipse. Issue 2 (24th December 2019)

• Record Type: Journal Article
• Authors: Wood, Tobias C.; Teixeira, Rui P. A. G.; Malik, Shaihan J.
• Is Part Of: Magnetic resonance in medicine. Volume 84:Issue 2(2020)
• Page Start: 857
• Page End: 865
• Publication Date: 2019-12-24
• Subjects: MT -- PLANET -- SSFP; Nuclear magnetic resonance -- Periodicals; Electron paramagnetic resonance -- Periodicals; 616.07548
• DOI: 10.1002/mrm.28149
• Languages: English
• ISSNs: 0740-3194

Abstract

Abstract : Purpose: To demonstrate that quantitative magnetization transfer (qMT) parameters can be extracted from steady‐state free‐precession (SSFP) data with no external T 1 map or banding artifacts. Methods: SSFP images with multiple MT weightings were acquired and qMT parameters fitted with a two‐stage elliptical signal model. Results: Monte Carlo simulations and data from a 3T scanner indicated that most qMT parameters could be recovered with reasonable accuracy. Systematic deviations from theory were observed in white matter, consistent with previous literature on frequency distribution effects. Conclusions: qMT parameters can be extracted from SSFP data alone, in a manner robust to banding artifacts, despite several confounds.