Dedifferentiated liposarcoma with abrupt transition of low-grade and high-grade dedifferentiation: A rare case report. (20th September 2021)

• Record Type: Journal Article
• Authors: Wen, Yang; He, Xianglei; Zhao, Ming
• Is Part Of: International journal of immunopathology and pharmacology. Volume 35(2021)
• Publication Date: 2021-09-20
• Subjects: dedifferentiation -- liposarcoma -- neoplasm -- histopathology -- magnetic resonance imaging; Immunopathology -- Periodicals; Pharmacology -- Periodicals; Inflammation -- Periodicals; 615.1
• DOI: 10.1177/20587384211048565
• Languages: English
• ISSNs: 0394-6320

Abstract

Dedifferentiated liposarcoma is a unique subtype of liposarcoma, which has obvious histological heterogeneity. In affected patients, the condition typically manifests as the dedifferentiation of high-grade histological morphology, but it may also manifest as the dedifferentiation of low-grade histological morphology. In some cases, unique histological or immunophenotypic characteristics are observed. We describe, herein, a rare case of dedifferentiated liposarcoma, in which the high-grade and low-grade dedifferentiated components coexisted with a relatively sharp transition in pathology.