Impulsivity traits in eyelid myoclonia with absences. (October 2021)

• Record Type: Journal Article
• Authors: Luca, Antonina; Giuliano, Loretta; Manna, Roberta; D'Agate, Concetta; Maira, Giulia; Sofia, Vito; Nicoletti, Alessandra; Zappia, Mario
• Is Part Of: Seizure. Volume 91(2021)
• Page Start: 393
• Page End: 396
• Publication Date: 2021-10
• Subjects: Impulsivity -- Eyelid myoclonia with absences -- Juvenile myoclonic epilepsy -- Barratt impulsiveness scale; Epilepsy -- Periodicals; Epilepsy -- Periodicals; Seizures -- Periodicals; Épilepsie -- Périodiques; Electronic journals; Electronic journals; 616.853
• DOI: 10.1016/j.seizure.2021.07.006
• Languages: English
• ISSNs: 1059-1311

Abstract

Highlights: EMA patients showed significantly higher impulsivity compared to healthy controls. EMA patients showed significantly higher impulsivity compared to patients with JME. Treatment with levetiracetam was associated with higher impulsivity in EMA patients. Abstract: Purpose: Eyelid myoclonia with absences (EMA) shares some clinical characteristics with juvenile myoclonic epilepsy (JME), in which impulsivity traits have been described. Aim of the study was to evaluate whether EMA patients could present a peculiar behavioural profile. Methods: Patients with EMA, JME and healthy controls (HCs) were enrolled. Subjects with intellectual quotient <80 were excluded from the study. All the enrolled subjects underwent the Italian version of the Barratt Impulsiveness Scale (BIS-11) and the three dimensions of impulsivity (motor, attentional-cognitive and nonplanning impulsivity) were considered. Results: Seventeen patients with EMA (12 females [70.6%], age 30.8±10 years), 29 patients with JME (17 females [58.6%], age 29.1±9.7 years) and 31 HCs (15 females [48.4%], age 27.6±5.8 years) were enrolled. Both EMA and JME patients presented a borderline significantly higher BIS total score than HCs ( p =0.064). EMA patients presented a significantly higher BIS nonplanning subscore than JME patients and HCs ( p =0.001). Conclusion: The study showed the presence of peculiar behavioral characteristics in EMA patients, slightly different from patients with JME.