Opportunities and challenges in microbial medium chain fatty acids production from waste biomass. (November 2021)

• Record Type: Journal Article
• Authors: Wu, Qinglian; Jiang, Yong; Chen, Ying; Liu, Min; Bao, Xian; Guo, Wanqian
• Is Part Of: Bioresource technology. Volume 340(2021)
• Publication Date: 2021-11
• Subjects: Medium chain fatty acids -- Caproate -- Chain elongation -- Reverse β-oxidation -- Fatty acid biosynthesis; Biomass -- Periodicals; Biomass energy -- Periodicals; Bioremediation -- Periodicals; Agricultural wastes -- Periodicals; Factory and trade waste -- Periodicals; Organic wastes -- Periodicals; Bioénergie -- Périodiques; Déchets agricoles -- Périodiques; Déchets industriels -- Périodiques; Déchets organiques -- Périodiques; Déchets (Combustible) -- Périodiques; 662.88
• DOI: 10.1016/j.biortech.2021.125633
• Languages: English
• ISSNs: 0960-8524

Abstract

Graphical abstract: Highlights: Both RBO and FAB pathways for MCFAs production were introduced and compared. Five strategies for MCFAs production from waste biomass were elaborated. Key production challenges, research progresses, and solutions were discussed. Future research perspectives and priorities were recommended. Abstract: Medium chain fatty acids (MCFAs) that produced from affordable waste biomass via chain elongation (CE) technology are recognized as the potential alternatives to part fossil-derived chemicals, contributing to the sustainable development of economy and environment. The purpose of this review is to provide comprehensive analyses on the opportunities and challenges of MCFAs production and application. First, both two microbial MCFAs synthesis pathways of reverse β-oxidation and fatty acid biosynthesis were introduced/compared in detail to give readers a thorough understanding of the CE process, with the expectation of further boosting MCFAs production by well distinguishing them. Furthermore, the six key MCFAs production bottlenecks, corresponding research progresses, and possible solutions were analyzed. Five major MCFAs production strategies with their production mechanism, performances, and characteristics were also critically assessed. Additionally, the commercial production status was introduced, and future alternative production mode and research priorities were also recommended.