A New Avenue to the Synthesis of Symmetrically Substituted Pyridines Catalyzed by Magnetic Nano–Fe3O4: Methyl Arenes as Sustainable Surrogates of Aryl Aldehydes. Issue 31 (20th August 2019)

• Record Type: Journal Article
• Authors: Gajaganti, Somaiah; Kumar, Dhirendra; Singh, Sundaram; Srivastava, Vandana; Allam, Bharat Kumar
• Is Part Of: ChemistrySelect. Volume 4:Issue 31(2019)
• Page Start: 9241
• Page End: 9246
• Publication Date: 2019-08-20
• Subjects: Methylarene -- Nano catalysis. -- TBHP -- TEMPO -- Substituted pyridine; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.201900289
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: A straightforward strategy has designed for the efficient synthesis of 2, 4, 6–triarylpyridines via a three component reaction of acetophenone, methyl arenes and ammonium acetate. The total transformation is successfully achieved using a magnetic nano–Fe3 O4 . The method developed is sustainable, using low cost feed stocks, operationally simple, and provide good to excellent yields. Abstract : A direct approach has developed for the efficient multicomponent synthesis of 2, 4, 6–triarylpyridines from an acetophenone, methyl arenes and ammonium acetate using a magnetic nano–Fe3 O4 . The present approach is sustainable, using cheap feed stocks, operationally simple, and enables good to excellent yields.