Dense fibrillar collagen is a master activator of invadopodia. (3rd May 2016)
- Record Type:
- Journal Article
- Title:
- Dense fibrillar collagen is a master activator of invadopodia. (3rd May 2016)
- Main Title:
- Dense fibrillar collagen is a master activator of invadopodia
- Authors:
- Artym, Vira V.
- Abstract:
- ABSTRACT: Tumor stroma is characterized by abnormal accumulation of dense fibrillar collagen, which promotes tumor progression and metastasis. However, the effect of desmoplastic collagen on cells has been unclear. Our recent findings demonstrate that dense fibrillar collagen activates a novel phosphosignaling mechanism for robust induction of invadopodia in tumor cells and normal fibroblasts.
- Is Part Of:
- Molecular & cellular oncology. Volume 3:Number 3(2016)
- Journal:
- Molecular & cellular oncology
- Issue:
- Volume 3:Number 3(2016)
- Issue Display:
- Volume 3, Issue 3 (2016)
- Year:
- 2016
- Volume:
- 3
- Issue:
- 3
- Issue Sort Value:
- 2016-0003-0003-0000
- Page Start:
- Page End:
- Publication Date:
- 2016-05-03
- Subjects:
- Cell-matrix interactions -- dense fibrillar collagen -- desmoplasia -- extracellular matrix -- invadopodia -- invadosomes -- integrin -- metastasis
Tumors -- Periodicals
Neoplasms
Periodicals
616.99 - Journal URLs:
- http://www.tandfonline.com/loi/kmco20#.VyIIeFL2aic ↗
http://www.tandfonline.com/ ↗ - DOI:
- 10.1080/23723556.2015.1035476 ↗
- Languages:
- English
- ISSNs:
- 2372-3556
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 18609.xml