Synthesis of Biogenic Silver Nanoparticles with Eco-Friendly Processes Using Ganoderma lucidum Extract and Evaluation of Their Theranostic Applications. (4th August 2021)

• Record Type: Journal Article
• Authors: Nguyen, Vinh Phu; Le Trung, Hieu; Nguyen, Thu Huong; Hoang, DongQuy; Tran, Thai Hoa
• Other Names: Yi Dong kee Academic Editor.
• Is Part Of: Journal of nanomaterials. Volume 2021(2021)
• Publication Date: 2021-08-04
• Subjects: Nanostructured materials -- Periodicals; Nanotechnology -- Periodicals; Nanomatériaux; Nanostructured materials; Nanotechnology; Nanostructures; Nanotechnology; Periodicals; Fulltext; Internet Resources; Periodicals; 620.115
• DOI: 10.1155/2021/6135920
• Languages: English
• ISSNs: 1687-4110

Abstract

Abstract : The green synthesis of silver nanoparticles (AgNPs) using plant extract, the cost-effective solution, and the abundance and environmental issue have been gaining much attention to scientists. Ganoderma lucidum (GL) commonly known as Lingzhi in Chinese and Reishi in Japanese, with a proven anticancer benefit, is discovered in the buffer zone of Bach Ma National Park, Nam Dong district, Thua Thien Hue province. In this work, the AgNPs were synthesized in a simple and effective biochemical reduction process using GL which is one of the biological organisms, as a reducing and stable agent. The optimum conditions of various experimental parameters such as pH, reaction time, concentration, and temperature were investigated. Obtained AgNPs were characterized by UV-Vis, FTIR, SEM, energy-dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and transmission electron microscopy (TEM). The effects of AgNP/GL materials and GL aqueous extraction on the antiproliferative activities of HepG2 and MCF-7 cells were studied. The novel AgNP/GL-based multicomponent suspension is a key compound that could find a good application in the medical and pharmaceutical sciences.