British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults. (27th September 2019)

• Record Type: Journal Article
• Authors: Lamb, Christopher Andrew; Kennedy, Nicholas A; Raine, Tim; Hendy, Philip Anthony; Smith, Philip J; Limdi, Jimmy K; Hayee, Bu'Hussain; Lomer, Miranda C E; Parkes, Gareth C; Selinger, Christian; Barrett, Kevin J; Davies, R Justin; Bennett, Cathy; Gittens, Stuart; Dunlop, Malcolm G; Faiz, Omar; Fraser, Aileen; Garrick, Vikki; Johnston, Paul D; Parkes, Miles; Sanderson, Jeremy; Terry, Helen; Gaya, Daniel R; Iqbal, Tariq H; Taylor, Stuart A; Smith, Melissa; Brookes, Matthew; Hansen, Richard; Hawthorne, A Barney
• Other Names: Arnott Ian author non-byline.; Barrett Kevin J author non-byline.; Beattie R Mark author non-byline.; Bloom Stuart author non-byline.; Bodger Keith author non-byline.; Brady Richard R author non-byline.; Brookes Matthew J author non-byline.; Brown Steven R author non-byline.; Butterworth Jeffrey R author non-byline.; Calvert Christopher R author non-byline.; Campbell Rachel author non-byline.; Creed Tom author non-byline.; Croft Nicholas M author non-byline.; Cummings Fraser author non-byline.; Davies R Justin author non-byline.; Devadason David author non-byline.; Dhar Anjan author non-byline.; Dipper Chris author non-byline.; Duncan Julie author non-byline.; Dunlop Malcolm author non-byline.; Durai Dharmaraj author non-byline.; Evans Martyn D author non-byline.; Faiz Omar author non-byline.; Fearnhead Nicola S author non-byline.; Ford Alexander C author non-byline.; Fraser Aileen author non-byline.; Garrick Vikki author non-byline.; Gaya Daniel R author non-byline.; Goodhand James author non-byline.; Hall Nigel author non-byline.; Hansen Richard author non-byline.; Harbord Marcus author non-byline.; Hawthorne A Barney author non-byline.; Hayee Bu'Hussain author non-byline.; Hearnshaw Sarah author non-byline.; Henderson Paul author non-byline.; Hendy Philip author non-byline.; Iqbal Tariq author non-byline.; Johnston Paul D author non-byline.; Kennedy Nicholas A author non-byline.; Lamb Christopher A author non-byline.; Limdi Jimmy K author non-byline.; Lindsay James O author non-byline.; Lobo Alan J author non-byline.; Lomer Miranda author non-byline.; Lovegrove Richard E author non-byline.; Mansfield John C author non-byline.; Mclaughlin Simon author non-byline.; Mountford Christopher G author non-byline.; Muhammed Rafeeq author non-byline.; Noor Nurulamin M author non-byline.; Panter Simon author non-byline.; Parkes Gareth C author non-byline.; Parkes Miles author non-byline.; Pinkney Thomas D author non-byline.; Probert Chris author non-byline.; Raine Tim author non-byline.; Russell Richard K author non-byline.; Rutter Matthew D author non-byline.; Samaan Mark A author non-byline.; Sanderson Jeremy D author non-byline.; Selinger Christian P author non-byline.; Shah Ashit author non-byline.; Short Steve J author non-byline.; Singh Baljit author non-byline.; Smith Philip J author non-byline.; Smith Melissa author non-byline.; Speight R Alexander author non-byline.; Stansfield Catherine author non-byline.; Steed Helen author non-byline.; Taylor Stuart A author non-byline.; Terry Helen author non-byline.; Tham Tony C author non-byline.; Thompson Nick P author non-byline.; Walker Gareth J author non-byline.; Wall Catherine L author non-byline.; Warusavitarne Janindra author non-byline.; Williams Gethin L author non-byline.; Wilson R Graeme author non-byline.; Wilson David C author non-byline.; Younge Lisa C author non-byline.;
• Is Part Of: Gut. Volume 68(2019)Supplement 3
• Page Start: s1
• Page End: s106
• Publication Date: 2019-09-27
• Subjects: Ulcerative colitis, UC -- colitis -- Crohn's disease, CD -- ileitis -- granuloma -- fistula -- stricture -- perianal -- inflammatory bowel disease, IBD -- pouch -- pouchitis -- guideline -- classification -- diagnosis -- monitoring -- endoscopy -- endoscopic -- colonoscopy -- sigmoidoscopy -- ultrasound -- magnetic resonance, MR -- computerised tomography, CT -- biomarker -- calprotectin -- management -- therapy -- surgery -- colectomy -- adult -- adolescent -- suppository -- enema -- 5-aminosalicylate -- 5-ASA -- mesalazine -- corticosteroid -- budesonide -- prednisolone -- hydrocortisone -- methylprednisolone -- thiopurine -- azathioprine -- mercaptopurine -- ciclosporin -- cyclosporine -- anti-TNF -- infliximab -- adalimumab -- integrin -- vedolizumab -- ustekinumab -- JAK -- janus kinase inhibator -- tofacitinib -- therapeutic drug monitoring -- anti-drug antibodies -- nutrition -- diet -- vitamin D -- anaemia -- antibiotics -- tuberculosis, TB -- cytomegalovirus -- CMV -- clostridium difficile -- cancer -- chemoprevention -- surveillance -- pregnancy -- fetus -- breastfeeding -- probiotic -- antibiotic -- faecal microbial transplant -- vaccine -- vaccination -- multidisciplinary team, MDT -- adherence -- self-management -- telephone clinic -- virtual clinic -- primary stress -- care -- shared care -- fatigue -- stress -- psychology -- psychotherapy -- cognitive behavioural therapy, CBT -- smoking; Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gutjnl-2019-318484
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease. Both represent chronic inflammation of the gastrointestinal tract, which displays heterogeneity in inflammatory and symptomatic burden between patients and within individuals over time. Optimal management relies on understanding and tailoring evidence-based interventions by clinicians in partnership with patients. This guideline for management of inflammatory bowel disease in adults over 16 years of age was developed by Stakeholders representing UK physicians (British Society of Gastroenterology), surgeons (Association of Coloproctology of Great Britain and Ireland), specialist nurses (Royal College of Nursing), paediatricians (British Society of Paediatric Gastroenterology, Hepatology and Nutrition), dietitians (British Dietetic Association), radiologists (British Society of Gastrointestinal and Abdominal Radiology), general practitioners (Primary Care Society for Gastroenterology) and patients (Crohn's and Colitis UK). A systematic review of 88 247 publications and a Delphi consensus process involving 81 multidisciplinary clinicians and patients was undertaken to develop 168 evidence- and expert opinion-based recommendations for pharmacological, non-pharmacological and surgical interventions, as well as optimal service delivery in the management of both ulcerative colitis and Crohn's disease. Comprehensive up-to-date guidance is provided regarding indications for, initiation and monitoring of immunosuppressive therapies, nutrition interventions, pre-, peri- and postoperative management, as well as structure and function of the multidisciplinary team and integration between primary and secondary care. Twenty research priorities to inform future clinical management are presented, alongside objective measurement of priority importance, determined by 2379 electronic survey responses from individuals living with ulcerative colitis and Crohn's disease, including patients, their families and friends.