Keeping autophagy in cheCK1. (3rd May 2016)
- Record Type:
- Journal Article
- Title:
- Keeping autophagy in cheCK1. (3rd May 2016)
- Main Title:
- Keeping autophagy in cheCK1
- Authors:
- Cheong, Jit Kong
Virshup, David M. - Abstract:
- Abstract: Mutant RAS-driven cancer cells cope with proliferative stress by increasing basal autophagy to maintain protein/organelle and energy homeostasis. We recently demonstrated that casein kinase 1 alpha (CK1α), a therapeutically tractable enzyme, is critical for fine-tuning the transcriptional regulation of mutant RAS-induced autophagy and the development of mutant RAS-driven cancers.
- Is Part Of:
- Molecular & cellular oncology. Volume 3:Number 3(2016)
- Journal:
- Molecular & cellular oncology
- Issue:
- Volume 3:Number 3(2016)
- Issue Display:
- Volume 3, Issue 3 (2016)
- Year:
- 2016
- Volume:
- 3
- Issue:
- 3
- Issue Sort Value:
- 2016-0003-0003-0000
- Page Start:
- Page End:
- Publication Date:
- 2016-05-03
- Subjects:
- Autophagy -- cancer -- casein kinase 1 -- phosphorylation -- RAS
Tumors -- Periodicals
Neoplasms
Periodicals
616.99 - Journal URLs:
- http://www.tandfonline.com/loi/kmco20#.VyIIeFL2aic ↗
http://www.tandfonline.com/ ↗ - DOI:
- 10.1080/23723556.2015.1045117 ↗
- Languages:
- English
- ISSNs:
- 2372-3556
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 18575.xml