A 1 YEAR AUDIT OF ENDOLUMINAL ULTRASOUND- GUIDED FINE NEEDLE ASPIRATION CYTOLOGY INVESTIGATIONS (EUS-FNA) : DIAGNOSTIC EFFICACY AND INPUT OF ON-SITE CYTOLOGICAL ASSESSMENT. (8th June 2013)

• Record Type: Journal Article
• Authors: Hegarty, S; Lioe, T; Mitchell, M; McNeice, A; Mainie, I
• Is Part Of: Gut. Volume 62(2013)Supplement 2
• Page Start: A34
• Page End: A35
• Publication Date: 2013-06-08
• Subjects: Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gutjnl-2013-305143.82
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : Introduction: EUS-FNA as an investigative technique for pancreatic lesions and deep-seated lymphadenopathy is now well established. We carried out an audit of our practice, in particular the decrease in insufficient or non-diagnostic specimens when adequacy is assessed at the time of procedure. Aims/Background: A total of 91 patients underwent EUS-FNA over a one-year period at the Belfast City Hospital where there are 2 weekly sessions performed by Gastrointestinal endoscopists on consecutive days one of which is attended by a consultant cytopathologist +/− cytotechnician for on-site cytological assessment. Method: The cytology reports from those patients who underwent an EUS-FNA in our institution were retreived from the files of the Cytology Department, and assessed for diagnosis, adequacy, and necessity for further investigations. Results: Overall, 19/94 (20.2%) of the cases were reported as benign while 31/94 (33%) were malignant. 9.5% (9/94) were equivocal and 20% of samples were inadequate for diagnosis. However the inadequate sample rate fell from 33% to 7% when one session was attended by cytologist assessing the sample on-site. Three quarters of the cases were of abdominal lesions including a majority of pancreatic masses and surrounding lymph nodes. 2 were of intramural gastric and 2 liver lesions. The remaining quarter were of mediastinal lesions or lymphadenopathy. 5 cases of granulomatous lymphadenitis and 1 case of malignant lymphoma were diagnosed cytologically. Conclusion: EUS-FNA is a well-tolerated investigative technique to obtain a tissue diagnosis for further management decisions but the presence of on-site cytological assessment to provide immediate feedback ensures a higher diagnostic yield and increases the cost-effectiveness of the procedure.