PWE-049 Small-Bowel Capsule Endoscopy with 360° Panoramic-View: Results of The First Multicenter, Observational, Study. (17th August 2016)

• Record Type: Journal Article
• Authors: Tontini, GE; Wiedbrauck, F; Cavallaro, F; Marino, R; Spina, L; McAlindon, ME; Koulaouzidis, A; Rondonotti, E; Pastorelli, L; Vecchi, M
• Is Part Of: Gut. Volume 65(2016)Supplement 1
• Page Start: A162
• Page End: A163
• Publication Date: 2016-08-17
• Subjects: Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gutjnl-2016-312388.295
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : Introduction: CapsoCam®SV (CapsoVision Inc, Saratoga, USA) is a new small bowel capsule (SBC) with "panoramic view", wire-free technology, and a long-lasting battery life. It is equipped with 4 high-frame rate cameras resulting in a high number of acquired frames. In previous studies, CapsoCam®SV showed comparable operative and diagnostic performance with frontal view SBCs. 1, 2 Methods: First multicenter study to assess the performance of CapsoCam®SV1 and SV2. Between January 2011 and November 2015, all consecutive patients undergoing SBC with CapsoCam® in 4 Italian, 2 British, and 1 German Institution(s) were included. Findings were classified according to their clinical significance, in line with Saurin classification, as P0: low probability; P1: intermediate probability; P2: high probability. 3 We defined SBC as "positive" when at least one P2 finding was identified. Results: We enrolled 172 patients (94 M; median age±SD: 68±17 years, range: 9–97 years). Of them, 142 were referred for obscure GI bleeding (32 overt/110 occult OGIB) and 28 for suspected (17) or established (2) Crohn's disease (CD). Median battery life was 16.4 h (range 3.7–23.4 h). System failure occurred in 4 (2%) cases for technical problems; incomplete enteroscopy in 16/168 (9%), including two structuring disorders (i.e. stricturing CD & SB adenocarcinoma) with spontaneous capsule excretion and one stricturing SB carcinoid with capsule retrieval at time of surgery.The ampulla of Vater was clearly identified in 34% cases. The overall diagnostic yield (DY; rate of positive tests) was 41%; 43% in OGIB and 30% in suspected CD. In a per-lesion analysis, overall 560 findings were detected (P0: 55, P1: 253, P2: 252). Most lesions were located in the small bowel (448/560: 80%); 48% of them were P2. Interestingly, 95/560 (17%) and 17/560 (3%) lesions were detected in the upper and in the lower GI tract, 34 and 12 of them being classified as P2, respectively. Conclusion: The first multicenter study conducted in the everyday clinical practice with CapsoCam®SV, and based on the largest series so far collected, showed that SBC with 360° panoramic-view is easy to use, reliable, and has comparable DY and safety profile to forward view SCE. References: 1 Friedrich K, et al . J Gastroenterol Hepatol 2013;28 (9):1496–501. 2 Pioche M, et al . Endoscopy 2014;46 (6):479–84. 3 Saurin JC, et al . Endoscopy 2003;35 (7):576–84. Disclosure of Interest: None Declared