In vivo stress relaxation of human scalp. (September 2019)

• Record Type: Journal Article
• Authors: Lear, William; Blattner, Collin M.; Mustoe, Thomas A.; Kruzic, Jamie J.
• Is Part Of: Journal of the mechanical behavior of biomedical materials. Volume 97(2019)
• Page Start: 85
• Page End: 89
• Publication Date: 2019-09
• Subjects: Human scalp -- Skin -- Creep -- Stress relaxation; Biomedical materials -- Periodicals; Biomedical materials -- Mechanical properties -- Periodicals; Biomedical materials; Biomedical materials -- Mechanical properties; Periodicals; Electronic journals; 610.28
• DOI: 10.1016/j.jmbbm.2019.05.015
• Languages: English
• ISSNs: 1751-6161

Abstract

Abstract: Objective: Conduct a first in vivo study on the large deformation stress relaxation behavior of the human scalp. Methods: This study was conducted during Mohs micrographic surgery of the scalp of 14 patients aged 59–90 with wounds initially ranging from 9 to 41 mm wide. The initial wound diameter was measured under zero applied force. Then, the force required to close each wound using a single size 1 nylon suture and a SUTUREGARD suture retention device was measured, after which the suture was then locked in the retention device at fixed displacement. At time points of 300 s, 600 s, and 1800 s, the suture retention device was released, and the wound opening was again recorded at zero force, and the force required to close the wound was recorded. Results: The average wound closure force relaxed by 44% and 65% after 300 s and 1800 s, respectively. Average wound width decreased 30% and 42%, after 300 s and 1800 s, respectively, due to creep deformation. Furthermore, all wounds relaxed to be below 15 N of closure force after 600 s, which is considered the maximum clinically acceptable force. A relaxation time of ∼270 s and a threshold force for creep of ∼ 5 N was found. Significance: Results of this study provide the first quantitative clinical guidance for efficient scalp closure of large wounds by creep deformation and stress relaxation. Furthermore, the methodology developed here can be used as a basis for future in vivo studies of the stress relaxation and creep deformation of human scalp, which in turn can provide data for the development and validation of constitutive models for scalp deformation. Graphical abstract: Image 1 Highlights: First in vivo study of stress relaxation and creep behavior of the human scalp. First quantitative clinical guidance for efficient scalp closure of large wounds. Novel methodology to develop constitutive models for in vivo scalp deformation.