Analysis of Numerous Androgen Disruptors in Fish by Gas Chromatography Tandem Mass Spectrometry. (22nd November 2019)

• Record Type: Journal Article
• Authors: Liu, Shaoying; Bian, Tianbin; He, Huali; Huang, Huang; Jin, Quan; Wang, Shuting; Zhu, Guonian
• Is Part Of: Journal of AOAC International. Volume 100:Number 3(2017)
• Page Start: 647
• Page End: 652
• Publication Date: 2019-11-22
• Subjects: Agricultural chemistry -- Periodicals; Food -- Analysis -- Periodicals; 543
• DOI: 10.5740/jaoacint.16-0283
• Languages: English
• ISSNs: 1060-3271

Abstract

Abstract: An improved analytical method was developed for the simultaneous quantification of numerous androgen disruptors—vinclozolin, dichlorodiphenyltrichloroethanes (DDTs), hexachlorocyclohexanes, chlordane, heptachlor, dieldrin, endrin, and aldrin—in fish, followed by GC with tandem MS (MS/MS). Extraction, cleanup, and MS/MS parameters of analytes were optimized. The LOQs of the analytes ranged from 0.3 to 3.7 μg/kg. Reasonable recoveries (73.7–119.2%) were demonstrated at different spike levels with RSDs lower than 12.2%. This method was applied for the analysis of the target analytes in fish samples sold in Hangzhou, China, and DDTs were found to be the predominant contaminants in fish samples.